Nanotechnology in the Advancement of Enhancing Bioavailability

Gaurav R. Kirdak1, Sanika S. Wasankar2, Chanchal S. Ingle3

1, 2, 3 Students at Vidyaniketan college of pharmacy, Anjangaon Surji, Amravati, Maharashtra 444705.

gauravkirdak25603@gmail.com

Address of correspondence:

Gaurav R. Kirdak

Student at Vidyaniketan college of Pharmacy,

Anjangaon Surji, Amravati, Maharashtra 444705

G-mail: gauravkirdak25603@gmail.com

ABSTRACT:The nanotechnology is defined as the science that deals with the manipulations of matter on a scale of 1 to 100 nanometers, where a material can exhibit unique properties; whereas the bioavailability is defined as the rate and extent to which an administered drug substance is absorber and becomes available at its intended biological site of action in body. There are several factors which resulting disturbance in the path of bioavailability such as solubility, dissolution rate, lipophilicity, molecular size, chemical stability, pka value, first-pass metabolism, gastrointestinal motility, and disease state, etc. there is a need to overcome the mentioned factors and it can made possible with the use of Nanoparticulate nanomedicine (NNM), Nanoformulations like nanoemulsion, nanosuspension, Solid self-emulsifying drug delivery systems, and solid lipid nanoparticles (SLN) i.e Nanotechnology.Keywords: Nanotechnology; Conventional and modern methodology, Quantum effect in nano –formulations; Challenges in adaptation of nanotechnology.