International Scientific Journal of Engineering and Management

An International Scholarly || Multidisciplinary || Open Access || Indexing in all major Database & Metadata
ISSN: 2583-6129

Impact Factor: 5.081

FORMULATION AND EVALUATION OF MOUTH DISSOLVING FILM OF CARIPRAZINE HYDROCHLORIDE

  • Version
  • Download 39
  • File Size 324.09 KB
  • File Count 1
  • Create Date 25 August 2023
  • Last Updated 25 August 2023

FORMULATION AND EVALUATION OF MOUTH DISSOLVING FILM OF CARIPRAZINE HYDROCHLORIDE

Chaudhari Kamlesh Prakash*, Gaurav Jain, Rakesh Patel

Faculty of Pharmacy, Dr. A.P.J. Abdul Kalam University, Indore (M.P.) - India

 

Abstract

Mouth dissolving film is now a days preferred route of drug administration due to patient compliance.  The developed film formulation is a patient-friendly formulation that would be useful for people who have difficulty of swallowing. The results have shown that the HPMC-K4M is good film former and shows bioadhesion property. In combination with PEG-400, it has shown promising fast drug release within 10 min. and good folding endurance. Hence a semi-synthetic cellulose derivative which is affordable and abundantly available can be used as a potential drug release modifier and also used to improve flexibility and processability in the mouth dissolving films. Successful formulation of Cariprazine mouth dissolving films may prevent first pass metabolism to a large possible extent. From the present study it can be concluded that HPMC-K4M based mouth dissolving films of Cariprazine can be successfully prepared with considerable good stability and improved bioavailability

 

Keywords: Mpouth dissolving, Cariprazine, Evaluation


Download

Author's Blog

What is the difference between a Research Paper and a Review Paper?

A research paper and a review paper are both scholarly documents, but they serve different purposes and have different characteristics.research...
Read More
Author's Blog

What is DOI?

A Digital Object Identifier (DOI) is a unique alphanumeric string that is used to identify and provide a persistent link...
Read More
Author's Blog

What do you need to do during production of your Research Paper?

During the production of a research paper, the following steps need to be taken: conducting research, organizing and analyzing data,...
Read More
Author's Blog

What are the advantages of publishing a research paper?

Publishing a research paper can have many advantages for researchers, including: Career advancement, professional recognition, opportunities for collaboration, increased visibility,...
Read More
Author's Blog

Ways to Support your Academic Wellbeing which preparing the Research Paper/Article

To support your academic wellbeing while publishing a research paper, it's important to set realistic goals, manage your time effectively,...
Read More
Author's Blog

How to improve your Research Paper writing Skills?

Read extensively: One of the best ways to improve your research paper skills is to read extensively in your field...
Read More
Author's Blog

Is DOI compulsory to publish a research paper in a Journal?

DOI is not strictly required to publish a research paper, but it is highly recommended. Basically, the International Scientific Journal...
Read More
Author's Blog

In what ways does research paper give weight to career development?

Publishing a research paper can give weight to a researcher's career development in several ways, such as: establishing oneself as...
Read More
Author's Blog

How to develop a Research Paper from Scratch

Developing a research paper involves several steps including: choosing a topic, conducting background research, formulating a research question or hypothesis,...
Read More
Author's Blog

How Plagiarism report plays crucial role in Research Paper Publication?

Plagiarism is a major concern in the academic and research community, as it undermines the integrity of the research and...
Read More