HPTLC analysis of Catharanthus roseus Lin. (Vinca rosea) (aerial part) methanolic extract

Author: Rabia Bashir, rabiabatt462@gmail.com

Department of Life Science (Zoology), PhD Scholar

Rabindranath Tagore university, Bhopal (M.P.),

India

Co-author: Dr. Pragya Shrivastava, shrivastavapragya10@gmail.com

Rabindranath Tagore university

Abstract

Vinca alkaloids represent a category of natural medications derived from the Madagascar periwinkle plant. These compounds are extracted from the pink-hued periwinkle, which is scientifically referred to as Catharanthus roseus L. They exhibit both blood sugar-lowering and cell-killing properties. These alkaloids have been employed in managing diabetes, high blood pressure, and as antiseptics. Additionally, they play a crucial role in cancer treatment. The alkaloids from Vinca rosea are highly regarded for their healing properties, especially in oncology. A high-performance thin layer chromatography (HPTLC) method was recognized as an efficient and simple approach for swiftly identifying active components and measuring specific flavonoids in Catharanthus roseus. Linn. In this research, HPTLC analysis was conducted on the methanolic extract was performed for its phytochemical profiling.

Keywords: Catharanthus roseus (Vinca rosea) HPTLC analysis, Soxhlet apparatus, therapeutic values, Methanolic extract, Chromatogram.